Added: Soren Corker - Date: 23.01.2022 10:42 - Views: 16750 - Clicks: 4550
A year-old woman who needed a liver transplant was disqualified from getting one because her urine kept testing positive for alcohol. But when the woman insisted she hadn't been drinking, her doctors didn't believe her — until one group of researchers made an important discovery, according to a case study published Tuesday in the Annals of Internal Medicine.
Here are 5 key tactics to attract and retain transplant patients. Her cirrhosis was so severe that she was placed on the liver transplant waitlist, the researchers said. According to the case study, the woman had ly visited another hospital but was denied a spot on the liver-transplant waitlist because her urine kept testing positive for alcohol. The woman insisted she hadn't been drinking, but her doctors believed she was lying to cover up an alcohol addiction. Instead of putting her on the transplant list, they enrolled the woman in an alcohol misuse treatment program.
The authors of the study, a group of researchers at UPMC, said their initial interactions with the patient "were similar. For one, even though the patient's urine had a high alcohol concentration, she showed no s of intoxication.
In addition, when the doctors drew the woman's blood and tested her plasma, they didn't find any traces of ethanol. They also tested her urine for ethyl sulfate and ethyl glucuronide, chemicals the body produces to metabolize alcohol, but neither of the chemicals showed up in the lab tests. What did show up in her urine test was a large amount of sugar and yeast, which both contribute to fermentation, according to report co-author Kenichi Tamama, an associate professor of pathology and medical director of UPMC's Clinical Toxicology Laboratory.
Tamama and the researchers decided to perform one more test. The researchers incubated one of the patient's fresh urine samples in the lab and found the samples became more alcoholic after they were left to ferment.
The doctors realized that a similar fermentation process may be happening in the woman's body. According to doctors, the yeast inside the patient's body was fermenting sugar in her bladder, which explained the ethanol showing up in her urine tests. Once doctors made the diagnosis, the woman was "reconsidered for liver transplantation," the researchers wrote.
According to the Washington Postit's not clear whether she will receive one. The woman's condition could be a new form of auto-brewery syndrome ABSthe researchers said. ABS is a condition in which microbes in the gastrointestinal tract convert carbs into alcohol. In this woman's case, fermentation was occurring in the bladder.
Some people with ABS can get drunk after eating carbs, but because the alcohol couldn't travel from the woman's bladder to her bloodstream, the woman never seemed intoxicated. The doctors proposed naming the woman's condition "urinary auto-brewery syndrome" or "bladder fermentation syndrome," Live Science reports.
While there have been other reported cases of ABS, some researchers have disputed whether the condition exists, according to the Post.
A review published in found that "to date none of the studies published supporting the theory have withstood close scrutiny. However, since the review, multiple case studies have documented suspected cases of the condition, the Post reports. In one case, a year-old man who was pulled over on suspicion that he'd been driving drunk said he had the condition.
At the hospital, his blood alcohol level was more than twice the legal limit, but a study published last year confirmed that fungi in the man's gut were brewing alcohol, making him seem intoxicated.
One study published in said that ABS is likely an "underdiagnosed medical condition. Current Article This woman hadn't been drinking.
So why did she have so much alcohol in her urine? February 26, This woman hadn't been drinking. Here are 5 key tactics to attract and retain transplant patients What follow-up tests revealed The patient came to the University of Pittsburgh Medical Center UPMC Presbyterian Hospital with cirrhosis of the liver and diabetes.
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A positive test without drinking?